发明名称 |
A BIOCOMPATIBLE, NON-BIODEGRADABLE, NON-TOXIC POLYMER USEFUL FOR NANOPARTICLE PHARMACEUTICAL COMPOSITIONS |
摘要 |
<p>The invention relates to a biocompatible, non-biodegradable, and non-toxic polymer of formula (I), comprising of three monomeric units, selected from 1-Vinylpyrrolidone (VP), N-Isopropylacrylamide (NIPAM), and ester of Maleic anhydride and Polyethylene glycol (MPEG), cross-linked with a bi-functional vinyl derivative, of high purity and substantially free of respective toxic monomeric contaminants, and a process for preparation thereof. The invention further relates to nanoparticulate pharmaceutical compositions of poorly water-soluble drugs or compounds comprising the polymer of the invention, which are safe, less-toxic and convenient for bedside administration to patients in need thereof. Furthermore, the invention relates to a highly selective method for preparation of nanoparticulate pharmaceutical compositions of poorly water-soluble drugs or compounds.</p> |
申请公布号 |
HK1123814(A1) |
申请公布日期 |
2012.12.28 |
申请号 |
HK20090103495 |
申请日期 |
2009.04.15 |
申请人 |
FRESENIUS KABI ONCOLOGY LIMITED |
发明人 |
BURMAN, ANAND, C.;MUKHERJEE, RAMA;KHATTAR, DHIRAJ;MULLICK, SANJOY;JAGGI, MANU;SINGH, MANOJ, KUMAR;KUMAR, MUKESH;PRUSTHY, DEEPAK;GUPTA, PAWAN, KUMAR;PRAVEEN, RAJENDRAN;SINGH, SHOBHIT |
分类号 |
C08F |
主分类号 |
C08F |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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