NOVEL USE OF RICE, RICE BRAN OR RICE HULL EXTRACT AS A HISTAMINE RECEPTOR ANTAGONIST

摘要

The present invention provides a novel usage of a rice, rice bran, or chaff extract as a histamine receptor antagonist. The rice, rice bran, or chaff extract is used as a natural antihistamine agent for preventing or treating allergic rhinitis; inflammatory bowel disease; asthma; bronchitis; vomiting; gastric and duodenal ulcer; gastroesophegeal reflux; sleep disorders; anxiety; and depression, and shows similar or improved effectiveness in reducing the time required for entering a hypnagogic state and increasing sleeping time, compared to diazepam, which is an existing drug used as a sleep inducing agent. The rice, rice bran, or chaff extract is a natural product and does not have side effects such as cognitive impairment, resistance, or dependency even with long-term use.