发明名称 METHODS OF USING SMALL COMPOUNDS TO ENHANCE MYELOID DERIVED SUPPRESSOR CELL FUNCTION FOR TREATING AUTOIMMUNE DISEASES
摘要 <p>Methods for enhancing the suppressive function of myeloid derived suppressor cells (MDSCs) for the treatment of autoimmune diseases using small compounds are disclosed. In certain aspects, the small compounds are glatiramer acetate and mitogen activated protein (MAP) kinase inhibitors. In other aspects, these methods include the administration of exogenous MDSCs or the use of endogenous MDSCs mobilized using stem cell mobilizers. In yet other aspects, compositions containing MDSCs and small compounds of the invention are provided.</p>
申请公布号 EP2515919(A2) 申请公布日期 2012.10.31
申请号 EP20100843546 申请日期 2010.12.21
申请人 MOUNT SINAI SCHOOL OF MEDICINE 发明人 CHEN, SHU-HSIA
分类号 A61K35/12;A61K31/135;A61K31/16;A61K38/45;A61P37/00 主分类号 A61K35/12
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