INHIBITORS OF CATECHOL O-METHYL TRANSFERASE AND THEIR USE IN THE TREATMENT OF PSYCHOTIC DISORDERS.
摘要
<p>The present invention relates to 4-pyridinone compounds which are inhibitors of catechol O-methyltransferase (COMT), and are useful in the treatment and prevention of neurological and psychiatric disorders and diseases in which COMT enzyme is involved. The present invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which COMT is involved.</p>
申请公布号
MX2012010188(A)
申请公布日期
2012.10.03
申请号
MX20120010188
申请日期
2011.02.28
申请人
MERCK SHARP & DOHME CORP.*
发明人
MANLEY, PETER, J.;WOLKENBERG, SCOTT;BARROW, JAMES C.;NANDA, KAUSIK K.;TROTTER, B. WESLEY;HARRISON, SCOTT T.;ZHAO, ZHIJIAN