发明名称 |
MET INHIBITORS FOR ENHANCING RADIOTHERAPY EFFICACY |
摘要 |
Met inhibitor and/or nucleotide sequence encoding a Met inhibitor for use in the treatment of patients suffering from a cancer for reducing and/or abrogating patients' resistance to radiotherapy, wherein the Met inhibitor is selected among: i) an anti-Met monoclonal antibody, ii) a genetically engineered antibody containing the complementarity determining regions (CDRs) of the anti-Met monoclonal antibody, and iii) a fragment of (i) or (ii) containing the complementarity determining regions (CDRs) of the anti-Met monoclonal antibody, or combinations thereof.
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申请公布号 |
CA2769991(A1) |
申请公布日期 |
2012.09.18 |
申请号 |
CA20122769991 |
申请日期 |
2012.03.01 |
申请人 |
METHERESIS TRANSLATIONAL RESEARCH SA |
发明人 |
BOCCACCIO, CARLA;COMOGLIO, PAOLO MARIA;PETRONZELLI, FIORELLA;DE SANTIS, RITA |
分类号 |
A61K39/395;A61P35/00;C07K14/71;C07K14/82;C07K16/30;C12N15/13 |
主分类号 |
A61K39/395 |
代理机构 |
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主权项 |
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地址 |
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