发明名称 |
INHIBITION OF MACROPHAGE-STIMULATING PROTEIN RECEPTOR (RON) AND METHODS OF TREATMENT THEREOF |
摘要 |
Disclosed is an antibody or fragment thereof that specifically binds to a human RON protein to treat diseases such as cancer. The invention further relates to a pharmaceutical composition comprising the antibody and a method for inhibiting angiogenesis, tumor growth, proliferation of tumor cells by means of the antibody. |
申请公布号 |
UA99633(C2) |
申请公布日期 |
2012.09.10 |
申请号 |
UA20100006208 |
申请日期 |
2008.11.21 |
申请人 |
IMCLONE LLC |
发明人 |
PEREIRA, DANIEL;O'TOOLE, JENNIFER |
分类号 |
C07K16/18;A61K39/395;C12N15/13 |
主分类号 |
C07K16/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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