MENINGOCOCCAL MULTIVALENT NATIVE OUTER MEMBRANE VESICLE VACCINE, METHODS OF MAKING AND USE THEREOF
摘要
The present technology provides vaccine compositions comprising native outer membrane vesicles (NOMVs) from at least one genetically modified strain of Neisseria which provides protective immunity to meningococcal disease, more preferably subtype B meningococcal disease. The present technology further provides methods of immunizing an animal or human against meningococcal disease comprising administering the vaccine composition of the present invention.
申请公布号
UA99659(C2)
申请公布日期
2012.09.10
申请号
UA20100015812
申请日期
2009.06.01
申请人
THE U.S.A., AS REPRESENTED BY THE SECRETARY OF THE ARMY, ON BEHALF OF WALTER REED ARMY
发明人
ZOLLINGER, WENDELL, DAVID;DONETS, MIKHAIL;SCHMIEL, DEBORAH;IONIN, BORIS;MARQUES, RYAN;MORAN, ELIZABETH, ELLEN