发明名称 |
VDAC1 COMPOSITIONS AND METHODS OF USE THEREOF FOR REGULATING APOPTOSIS |
摘要 |
The present invention relates generally to the mitochondrial protein, voltage-dependent anion channel (VDAC), polynucleotides encoding same and variants thereof, as well as peptide fragments, peptide derivatives and analogs. In particular, the present invention is directed to VDAC1 and specific amino acid and polynucleotide sequences thereof useful in inducing or regulating apoptosis and to pharmaceutical compositions comprising same useful in the treatment of diseases associated with aberrant apoptosis.
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申请公布号 |
US2012214741(A1) |
申请公布日期 |
2012.08.23 |
申请号 |
US201213397548 |
申请日期 |
2012.02.15 |
申请人 |
SHOSHAN-BARMATZ VARDA;ABU-HAMAD SALAH;ARZOINE LAETITIA;ZAID HILAL;BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY LTD. |
发明人 |
SHOSHAN-BARMATZ VARDA;ABU-HAMAD SALAH;ARZOINE LAETITIA;ZAID HILAL |
分类号 |
A61K38/17;A61K38/10;A61P19/02;A61P29/00;A61P31/12;A61P35/00;A61P35/02;A61P37/06;C07K7/08;C07K14/435 |
主分类号 |
A61K38/17 |
代理机构 |
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主权项 |
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地址 |
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