发明名称 |
STABLE AQUEOUS MIA/CD-RAP FORMULATIONS |
摘要 |
The present invention relates to stable aqueous formulations comprising at least 5 mg/mL CD-RAP and a charged amino acid, said amino acid preferably having a net charge at a pH between about 6 and 8. The ingredients of the formulation preferably provide stability over repeated freeze-thaw cycles. In a preferred aspect, the formulation is for use in therapy, preferably for use in the treatment of inflammatory disorders, preferably osteoarthritis. Furthermore, a kit comprising the formulation of the invention is provided. |
申请公布号 |
WO2011134979(A9) |
申请公布日期 |
2012.08.16 |
申请号 |
WO2011EP56622 |
申请日期 |
2011.04.27 |
申请人 |
SCIL TECHNOLOGY GMBH;HELLERBRAND, KLAUS;SIGL, RAINER |
发明人 |
HELLERBRAND, KLAUS;SIGL, RAINER |
分类号 |
C07K14/78;A61K9/00;A61K38/18;A61K47/22;C07K14/47 |
主分类号 |
C07K14/78 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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