发明名称 METHOD OF PREVENTION AND TREATMENT OF LIVER DISEASE WITH APPLICATION OF RECEPTOR A2B ANTAGONISTS
摘要 FIELD: medicine, pharmaceutics. ^ SUBSTANCE: group of inventions relates to field of medicine. Method of treatment and prevention of liver fibrosis includes peroral introduction to mammal of therapeutically efficient amount of antagonist of adenosine receptor A2B - 3-ethyl-1-propyl-8-(1-{[3-(trifluormethyl)phenyl]methyl}pyrazol-4-yl)-1,3,7-trihydropurine-2,6-dione. Method of reducing hepatotoxic side effects of chemical therapy or radiotherapy includes peroral introduction to mammal who underwent such treatment of therapeutically efficient amount of antagonist of adenosine receptor A2B - 3-ethyl-1-propyl-8-(1-{[3-(trifluormethyl)phenyl]methyl}pyrazol-4-yl) -1,3,7-trihydropurine-2,6-dione. ^ EFFECT: application of claimed group of inventions is efficient for prevention and treatment of liver diseases. ^ 6 dwg, 21 ex
申请公布号 RU2457842(C2) 申请公布日期 2012.08.10
申请号 RU20080137279 申请日期 2007.03.16
申请人 GAJLID PALO AL'TO, INK. 发明人 TSZEN DEHVAN';CHZHUN KHUNJAN';BELARDINELLI LUIS
分类号 A61K31/522;A61P1/16 主分类号 A61K31/522
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