| 摘要 |
Wound closure apparatus (30) is provided including a body (32) having an elongated, lowermost force-transmitting surface (72) operable to be placed in a proximal, external, wound-closing position on a patient, together with a force-exerting assembly (34) coupled with the body (32) and operable to exert a downwardly directed force serving to generate wound-closing pressure against the patient's tissue. The force-transmitting surface (72) is preferably three-dimensionally asymmetric so that forces of different magnitude are exerted at different locations along the length of the surface (72). The apparatus (30) is especially designed for the closure of wounds attendant to endovascular interventions, e.g., a femoral artery puncture wound (138) incident to percutaneous cardiac intervention (PCI), wherein the wound (138) has an insertion site (142), an oblique tract (144) within the patient's tissue (140), and an arteriotomy (146). In such uses, the apparatus (30) is positioned and operated so as to partially close the patient's artery (148) upstream of the arteriotomy (146), thereby lessening the patient's blood flow at the arteriotomy (146). The apparatus (30) is capable of quickly effecting wound closure with a time-to-ambulation (TTA) of approximately 60 minutes, and a very low complication rate. The apparatus and methods hereof may also be used for the closure of wounds created during venous intervention procedures. |
