| 发明名称 |
METHODS FOR SCREENING FOR AGENTS THAT MODULATE HEPATOCELLULAR CARCINOMA DEVELOPMENT |
| 摘要 |
The present invention is directed to methods using transgenic mice or transgenic cell cultures comprising a stably integrated transgene encoding FGF19 to screen for biologically active agents that modulate hepatocellular carcinoma development.
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| 申请公布号 |
CA2486252(C) |
申请公布日期 |
2012.07.24 |
| 申请号 |
CA20032486252 |
申请日期 |
2003.06.04 |
| 申请人 |
GENENTECH, INC. |
发明人 |
FRENCH, DOROTHY;ASHKENAZI, AVI J.;DESNOYERS, LUC;STEPHAN, JEAN-PHILIPPE F. |
| 分类号 |
A01K67/027;C12Q1/68;A61K31/7088;A61K35/12;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P1/00;A61P1/16;A61P1/18;A61P11/00;A61P13/10;A61P15/00;A61P17/00;A61P25/00;A61P35/00;A61P35/02;C07K14/00;C07K14/47;C07K14/50;C07K16/18;C07K16/46;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/09;C12N15/85;C12P21/02;C12P21/08;C12Q1/00;C12Q1/02;G01N33/15;G01N33/50;G01N33/574 |
主分类号 |
A01K67/027 |
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