| 发明名称 |
USE OF IL-15 TO INCREASE THYMIC OUTPUT AND TO TREAT LYMPHOPENIA |
| 摘要 |
The present invention provides method for promoting the maturation and export of T cells from thymic tissue by contacting the thymic tissue with supraphysiological levels of interleukin (IL)-15. The present invention also provides methods for preventing, alleviating, reducing, and/or inhibiting lymphopenia or peripheral depletion of lymphocytes in a patient in need thereof by administering to the patient IL-15. |
| 申请公布号 |
EP2464377(A1) |
申请公布日期 |
2012.06.20 |
| 申请号 |
EP20100752466 |
申请日期 |
2010.08.13 |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASNATIONAL INSTITUTES OF HEALTH OFFICE OF TECHNOLOGY TRANSFER |
发明人 |
PAVLAKIS, GEORGE N.;FELBER, BARBARA K.;VALENTIN, ANTONIO;BERGAMASCHI, CRISTINA |
| 分类号 |
A61K38/20;A61K38/17;A61K45/06;A61K47/48;A61K48/00;A61P37/02;C07K14/54;C07K14/715 |
主分类号 |
A61K38/20 |
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