摘要 |
<p>A system for remote ischemic preconditioning, the system comprising:
a cuff configured to retract about a limb of a subject;
an actuator connected to the cuff and that, when actuated, causes the cuff to contract about the limb of the subject to reduce blood flow therethrough;
a controller that controls the actuator according to a treatment protocol that includes a plurality of treatment cycles, each treatment cycle comprising;
cuff actuation, during which the actuator contracts the cuff about the limb of the subject to a pressure that occludes blood flow through the limb;
an ischemic duration, during which the actuator maintains the cuff contracted about the limb at a set point to occlude blood flow through the limb, the ischemic duration lasting for at least five seconds;
cuff release, during which the actuator releases the cuff to allow blood flow through the limb; and
a reperfusion duration, during which the cuff is maintained about the limb in a relaxed state to allow blood flow through the limb, the reperfusion duration lasting for at least one minute; and
a transducer that identifies reperfusion through the limb, wherein the controller receives a signal from the transducer during the ischemic phase to confirm a lack of reperfusion.</p> |