发明名称 |
Recombinant B. pseudomallei Adhesin Protein and Methods and Uses Thereof |
摘要 |
Isolated and/or recombinant adhesin polypeptides from Burkholderia pseudomallei are provided, which are used as vaccines. Genetic constructs comprising nucleic acid sequences encoding such polypeptides are also provided. Vectors comprising such constructs have been prepared and used for transforming host cells for producing the polypeptides of the invention. Antibodies to such polypeptides are also provided. Such antibodies can be used to detect the presence of B. pseudomallei or B. mallei. Methods of treating or preventing Burkholderia infection
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申请公布号 |
US2012087924(A1) |
申请公布日期 |
2012.04.12 |
申请号 |
US201113252677 |
申请日期 |
2011.10.04 |
申请人 |
STRATILO CHAD WESLEY;JAGER SCOTT JAMES;HER MAJESTY THE QUEEN IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF NATIONAL DEFENSE |
发明人 |
STRATILO CHAD WESLEY;JAGER SCOTT JAMES |
分类号 |
A61K39/40;A61P31/04;C07K16/12;C12N1/19;C12N1/21;C12N7/01 |
主分类号 |
A61K39/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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