发明名称 |
Identification, Optimization and Use of Cryptic HLA-A24 Epitopes for Immunotherapy |
摘要 |
The present invention pertains to methods for identifying a HLA-A*2402-restricted cryptic epitope in an antigen, and for increasing its immunogenicity, in order to obtain HLA-A*2402-restricted epitopes able to trigger an immune response against HLA-A*2402-restricted cryptic epitopes. Isolated peptides consisting of cryptic or optimized HLA-A*2402-restricted epitopes are provided.
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申请公布号 |
US2012082692(A1) |
申请公布日期 |
2012.04.05 |
申请号 |
US200913258227 |
申请日期 |
2009.04.02 |
申请人 |
KOSMATOPOULOS KOSTANTINOS(KOSTAS);MENEZ-JAMET JEANNE;VAXON BIOTECH |
发明人 |
KOSMATOPOULOS KOSTANTINOS(KOSTAS);MENEZ-JAMET JEANNE |
分类号 |
A61K39/00;A61P37/04;C07H21/04;C07K1/00;C07K2/00;C07K7/06;C07K19/00;G01N33/566 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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