发明名称 |
Use of IL-15 to increase thymic output and to treat lymphopenia |
摘要 |
The present invention provides method for promoting the maturation and export of T cells from thymic tissue by contacting the thymic tissue with supraphysiological levels of interleukin (IL)-15. The present invention also provides methods for preventing, alleviating, reducing, and/or inhibiting lymphopenia or peripheral depletion of lymphocytes in a patient in need thereof by administering to the patient IL-15. |
申请公布号 |
AU2010282280(A1) |
申请公布日期 |
2012.02.09 |
申请号 |
AU20100282280 |
申请日期 |
2010.08.13 |
申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY OF THE DEPARTMENT OFHEALTH AND HUMAN SERVICES |
发明人 |
PAVLAKIS, GEORGE N.;FELBER, BARBARA K.;VALENTIN, ANTONIO;BERGAMASCHI, CRISTINA |
分类号 |
A61K38/20;A61K47/48;A61K48/00;A61P37/04 |
主分类号 |
A61K38/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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