| 摘要 |
FIELD: medicine. ^ SUBSTANCE: group of inventions relates to compositions for oral cavity care, containing mucoadhesive polymers, and to their application for reducing symptoms associated with xerotomia. Claimed compositions contain cation-sensitive mucoadhesive polymer; and cation-releasing compound; where cation-releasing compound is incapsulated into degradable capsule. Examples of mucoadhesive cation-sensitive polymer materials include gellan gum and carageenan. Cation-releasing compounds include salts, such as calcium salts, sodium salts, salts of metals, preferably calcium chloride. Materials, applied for incapsulation of cation-releasing compounds include silicon, copolymer of lactic and glycolic acids (PLGA), alkylcellulose polymer. Composition for oral cavity care can be made, for instance, in form of liquid for mouthwash, spray for oral cavity care or toothpaste. ^ EFFECT: claimed compositions can be used for reduction and/or prevention of "dry mouth". ^ 12 cl |
