摘要 |
<p>The present invention relates to compound (I) wherein: means a pyridazine, a pyrimidine or a pyrazine group, R independently represent a hydrogen atom, a halogen atom or a group chosen among a CN group, a hydroxyl group, a COOR group, a (C-C)fluoroalkyl group, a (C-C)fluoroalkoxy group, a NO group, a NRR group, a (C-C)alkoxy group, a phenoxy group and a (C-C)alkyl group, said alkyl being optionally mono-substituted by a hydroxyl group, n is 1, 2 or 3, n is 1 or 2, R is a hydrogen atom, a halogen atom or a group chosen among a (C-C)alkyl group,, a hydroxyl group, a COOR group, a NO group, a NRR group, a morpholinyl or a morpholino group, a N-methylpiperazinyl group, a (C-C)fluoroalkyl group, a (C1-C4)alkoxy group and a CN group, Z is N or C, Y is N or C, X is N or C, W is N or C, T is N or C, U is N or C, for use as an agent for preventing, inhibiting or treating cancer. Some of said compounds are new and also form part of the invention.</p> |
申请人 |
INSTITUT CURIE;UNIVERSITE MONTPELLIER 2;SOCIETE SPLICOS;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
ROUX, PIERRE;MAHUTEAU, FLORENCE;NAJMAN, ROMAIN;TAZI, JAMAL;GADEA, GILLES |