摘要 |
<p>The present invention relates to pyrazole derivatives and to processes for their synthesis as 5 -lipoxygenase (5-LO) inhibitors. The present invention also relates to pharmacological compositions containing these pyrazole derivatives, as well as methods of treating bronchial asthma, chronic obstructive pulmonary disease, rheumatoid arthritis, multiple sclerosis, Type I diabetes, psoriasis, allograft rejection, inflammatory bowel disease, ulcerative colitis, acne, atherosclerosis, cancer, pruritis, allergic rhinitis and other inflammatory and/or autoimmune disorders.</p> |
申请人 |
RANBAXY LABORATORIES LIMITED;VERMA, ASHWANI, KUMAR;MALHOTRA, SANJAY;MARIMGANTI, SRINIVASA;BHATNAGAR, PRADIP, KUMAR;CLIFFE, IAN, A.;RAY, ABHIJIT;GUPTA, SUMAN;SRIVASTAVA, PUNIT;DASTIDAR, SUNANDA, GHOSH |
发明人 |
VERMA, ASHWANI, KUMAR;MALHOTRA, SANJAY;MARIMGANTI, SRINIVASA;BHATNAGAR, PRADIP, KUMAR;CLIFFE, IAN, A.;RAY, ABHIJIT;GUPTA, SUMAN;SRIVASTAVA, PUNIT;DASTIDAR, SUNANDA, GHOSH |