发明名称 |
METHODS FOR PRODUCING MIXTURES OF ANTIBODIES |
摘要 |
The invention relates to a method for producing a mixture comprising two or more different antibodies in a single recombinant host cell. In one embodiment, a mixture of different monovalent antibodies is produced. In another embodiment, a mixture of monovalent and bivalent antibodies is produced. The invention also relates to mixtures of antibodies obtainable by the method of the invention and to light chain sequences that are particularly useful in the method of the invention. |
申请公布号 |
EP2389392(A1) |
申请公布日期 |
2011.11.30 |
申请号 |
EP20100701360 |
申请日期 |
2010.01.26 |
申请人 |
GENMAB A/S |
发明人 |
PARREN, PAUL;NEIJSSEN, JOOST J.;LABRIJN, ARAN FRANK;SCHUURMAN, JANINE;VINK, TOM;VAN DE WINKEL, JAN;LOVERIX, STEFAN;LASTERS, IGNACE |
分类号 |
C07K16/00;A61K39/395;A61P35/00;C07K16/28;C07K16/32 |
主分类号 |
C07K16/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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