发明名称 |
Cationic lipid-mediated enhancement of nucleic acid immunization of cats |
摘要 |
The present invention relates to a method to introduce a nucleic acid molecule into a felid by administration of a nucleic acid-cationic lipid complex composition. The method includes the step of administering to the felid, by a parenteral route, a nucleic acid-cationic lipid complex to elicit and/or enhance an immune response. In one embodiment, this method enhances the immune response in a felid compared to a method in which a naked DNA vaccine is administered to a felid. Also provided is a method to deliver a nucleic acid to a felid. This method comprises parenterally administering to the felid a composition that includes a nucleic acid molecule complexed with a cationic lipid.
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申请公布号 |
US8029776(B2) |
申请公布日期 |
2011.10.04 |
申请号 |
US20070866558 |
申请日期 |
2007.10.03 |
申请人 |
HESKA CORPORATION |
发明人 |
HAYNES JOEL R.;WONDERLING RAMANI S.;STINCHCOMB DAN T. |
分类号 |
A61K39/21;A61K39/00;A61K39/002;A61K39/02;A61K39/12;A61K39/125;A61K39/205;A61K39/215;A61K39/245;A61K39/255;A61K39/265;A61K39/27;A61K39/385;A61K39/39;A61K45/00;A61K47/00;A61K47/44;A61K48/00;C07H21/04;C07H23/00;C12P21/06 |
主分类号 |
A61K39/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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