发明名称 |
ECTOCORNEA-LIKE SHEET AND METHOD OF CONSTRUCTING THE SAME |
摘要 |
It is intended to provide a transplantation material applicable to ocular surface diseases with a need for ectocornea transplantation (i.e., an ectocornea-like sheet). Oral mucosal epithelial cells are inoculated onto an amnion and then cultured in the coexistence of supporter cells. When a layered structure of the oral mucosal epithelial cells is formed, the outermost layer is brought into contact with air, thereby inducing differentiation. Thus, an ectocornea-like sheet having an oral mucosal epithelial cell layer on the amnion is obtained. |
申请公布号 |
EP1454600(B1) |
申请公布日期 |
2011.08.31 |
申请号 |
EP20020780078 |
申请日期 |
2002.11.13 |
申请人 |
ARBLAST CO., LTD. |
发明人 |
NAKAMURA, TAKAHIRO;KINOSHITA, SHIGERU |
分类号 |
A61F2/14;A61L27/36;A61L27/38;A61L27/54;C12N5/08 |
主分类号 |
A61F2/14 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|