发明名称 |
BISMUTH-THIOLS AS ANTISEPTICS FOR BIOMEDICAL USES, INCLUDING TREATMENT OF BACTERIAL BIOFILMS AND OTHER USES |
摘要 |
Compositions and methods, including novel homogeneous microparticulate suspensions, are described for treating natural surfaces that contain bacterial biofilm, including unexpected synergy or enhancing effects between bismuth-thiol (BT) compounds and certain antibiotics, to provide formulations including antiseptic formulations. Previously unpredicted antibacterial properties and anti-biofilm properties of disclosed BT compounds and BT compound-plus-antibiotic combinations are also described, including preferential efficacies of certain such compositions for treating certain gram-positive bacterial infections, and distinct preferential efficacies of certain such compositions for treating certain gram-negative bacterial infections. |
申请公布号 |
WO2011097347(A2) |
申请公布日期 |
2011.08.11 |
申请号 |
WO2011US23549 |
申请日期 |
2011.02.03 |
申请人 |
MICROBION CORPORATION;BAKER, BRETT, HUGH, JAMES |
发明人 |
BAKER, BRETT, HUGH, JAMES |
分类号 |
A61K31/29;A61K9/14;A61K9/70;A61K31/7036;A61K31/704;A61K31/7042;A61P17/00;A61P31/04 |
主分类号 |
A61K31/29 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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