RECOMBINANT INACTIVATED VIRAL VECTOR VACCINE.

摘要

A vaccine is described comprising an inactivated viral vector having inserted therein an exogenous nucleotide sequence encoding for a disease of interest, together with a pharmaceutically acceptable vehicle, adjuvant or excipient, providing due protection against the disease of interest through use of a concentration of the viral vector similar to that required for an active virus vaccine based on the same viral vector. Principally viral vectors of paramyxovirus or adenovirus are described.