摘要 |
Disclosed is a 1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)compound of the formula (I) wherein Q combined together with the carbon atoms to which it is attached form an aromatic, or a aliphatic carbocyclic or heterocyclic ring; R1, R2, R3, R4 and R5 is as defined in the specification. Also disclosed is the use of said compound for the treatment of insulin resistance, glucose intolerance, type 2 diabetes, diabetic renal insufficiency, diabetic nephropathy, diabetic retinopathy or obesity.
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申请人 |
NOVARTIS AG |
发明人 |
BARNES, DAVID;BEBERNITZ, GREGORY RAYMOND;COPPOLA, GARY MARK;NAKAJIMA, KATSUMASA;STAMS, TRAVIS;TOPIOL, SIDNEY WOLF;VEDANANDA, THALATHTHANI RALALAGE;WAREING, JAMES RICHARD |