发明名称 |
THERAPEUTIC AGENT (Y - 39983 ) FOR CORNEAL ENDOTHELIAL DYSFUNCTION |
摘要 |
The present invention aims to provide a means for effectively and conveniently treating diseases wherein corneal endothelial cells poor in proliferative capacity in vivo are damaged. The present invention provides a therapeutic agent for corneal endothelial dysfunction containing (R) - ( + ) -N- (lH-pyrrolo [2, 3 -b] pyridin-4-yl) -4- (1 -aminoethyl) benzamide <Y- 39983> or a pharmacologically acceptable salt thereof (compound (Ia) ) as active ingredient, an agent for promoting adhesion of corneal endothelial cells, containing compound (Ia), a culture medium for corneal endothelial cells, containing the agent for promoting adhesion, an implant for corneal endothelial keratoplasty, containing corneal endothelial cells, scaffold and compound (Ia), and a production method of a corneal endothelial preparation, including a step of cultivating corneal endothelial cells using the culture medium.
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申请公布号 |
CA2785851(A1) |
申请公布日期 |
2011.07.07 |
申请号 |
CA20102785851 |
申请日期 |
2010.12.28 |
申请人 |
MITSUBISHI TANABE PHARMA CORPORATION;SENJU PHARMACEUTICAL CO., LTD. |
发明人 |
TAKAHASHI, HIROAKI;SAKAMOTO, YUJI;KIDA, TETSUO;TARUI, TAKESHI |
分类号 |
A61K31/437;A61K9/00;A61P27/02;A61P43/00 |
主分类号 |
A61K31/437 |
代理机构 |
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