发明名称 Process and methods for the preparation of optically active cis-2-hydroxymethyl-4- (cytosin-1'-yl)-1,3-oxathiolane or pharmaceutically acceptable salts thereof
摘要 There is provided a method for resolving a compound of formula III, in the cis configuration: There is also provided a process for producing optically active compound of formula I or II: wherein: R1, R2, R3 are as defined herein, the method and process involving the production, recovery and conversion of diastereomeric salts.
申请公布号 US7968703(B2) 申请公布日期 2011.06.28
申请号 US20050073020 申请日期 2005.03.07
申请人 SHIRE CANADA INC. 发明人 CIMPOIA ALEX;SIMION DAN
分类号 C07D411/04;A61K31/506;A61K31/513;A61K31/7072;A61P31/18;C07D239/47 主分类号 C07D411/04
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