Serum bactericidal assay for N. meningitidis specific antisera
摘要
The present invention relates to the field of Serum Bactericidal Activity (SBA) assays for Gram negative bacteria, in particular N. meningitidis. The SBA assay is the most important method for measuring functional activity of serum antibodies against meningococcus. In order to determine whether a subject or a population is seropositive against invasive meningococcus the SBA test should ideally be both sensitive and specific. The inventors have found the standard N. meningitidis serotype A and W SBAs can be significantly improved in this regard.
申请公布号
EP2336777(A1)
申请公布日期
2011.06.22
申请号
EP20100179015
申请日期
2005.09.05
申请人
GLAXOSMITHKLINE BIOLOGICALS S.A.
发明人
DE VLEESCHAUWER, ISABEL;DURANT, NATHALIE;POOLMAN, JAN;WEYNANTS, VINCENT