| 摘要 |
Compounds for treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the compounds are of formula (I):
where x y, W, V, R 2 , R 3 , R 4 , R 5 , R 6 , R 6a , R 7 , R 7a , R 8 , R 8a , R 9 and R 9a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed. |
| 申请人 |
XENON PHARMACEUTICALS INC. |
发明人 |
ABREO, MELWYN;CHAFEV, MIKHAIL;CHAKKA, NAGASREE;CHOWDHURY, SULTAN;FU, JIAN-MIN;GSCHWEND, HEINZ, W.;HOLLADAY, MARK, W.;HOU, DUANJIE;KAMBOJ, RAJENDER;KODUMURU, VISHNUMURTHY;LI, WENBAO;LIU, SHIFENG;RAINA, VANDNA;SUN, SENGEN;SUN, SHAOYI;SVIRIDOV, SERGUEI;TU, CHI;WINTHER, MICHAEL, D.;ZHANG, ZAIHUI |
