摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method and apparatus for introducing materials capable of forming in situ that avoid premature gelling and/or clogging of a dispensing or delivery device. <P>SOLUTION: The delivery device 10 includes at least one lumen; a means for aiding in expelling materials from the lumen; and an opening through which the materials may be expelled from the delivery device 10 in vivo. At least a part of a surface of the delivery device 10 has a surface functionality capable of modulating the pH of a microenvironment near the surface. <P>COPYRIGHT: (C)2011,JPO&INPIT |