M-CSF-specific monoclonal antibody and uses thereof
摘要
<p>M-CSF-specific RX1-based or RX-1 derived antibodies are provided, along with pharmaceutical compositions containing such antibody, kits containing a pharmaceutical composition, and methods of preventing and treating bone loss in a subject afflicted with an osteolytic disease.</p>
申请公布号
EP2311873(A1)
申请公布日期
2011.04.20
申请号
EP20100178085
申请日期
2005.01.06
申请人
NOVARTIS VACCINES AND DIAGNOSTICS, INC.;XOMA TECHNOLOGY LTD.
发明人
LIU, CHENG;ZIMMERMAN, DEBORAH LEE;HARROWE, GREGORY MARTIN;KOTHS, KIRSTON;KAVANAUGH, WILLIAM MICHAEL;LONG, LI;CALDERON-CACIA, MARIA;HORWITZ, ARNOLD H.