| 发明名称 |
Compounds and methods for inhibiting the interaction of BCL proteins with binding partners |
| 摘要 |
The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.
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| 申请公布号 |
US7928244(B2) |
申请公布日期 |
2011.04.19 |
| 申请号 |
US20070842581 |
申请日期 |
2007.08.21 |
| 申请人 |
INFINITY DISCOVERY, INC. |
发明人 |
CASTRO ALFREDO C.;DEPEW KRISTOPHER M.;GROGAN MICHAEL J.;JOHANNES CHARLES W.;HOLSON EDWARD B.;HOPKINS BRIAN T.;KEANEY GREGG F.;KONEY NII O.;LIU TAO;MANN DAVID A.;NEVALAINEN MARTA;PELUSO STEPHANE;PEREZ LAWRENCE B.;SNYDER DANIEL A.;TIBBITTS THOMAS T. |
| 分类号 |
C07D261/02;A61K31/42 |
主分类号 |
C07D261/02 |
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