| 发明名称 |
PROCESS FOR THE PREPARATION OF HIGH PURITY SUNITINIB AND ITS PHARMACEUTICALLY ACCEPTABLE SALT |
| 摘要 |
<p>The present invention relates to an improved process for the preparation of N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide-Sunitinib base of formula (I) and its pharmaceutically acceptable malate salt of formula (I(a)).</p> |
| 申请公布号 |
KR20110036055(A) |
申请公布日期 |
2011.04.06 |
| 申请号 |
KR20117001593 |
申请日期 |
2008.11.17 |
| 申请人 |
NATCO PHARMA LIMITED |
发明人 |
KONDURI SRINIVASA KRISHNA MURTHY;ADIBHATLA KALI SATYA BHUJANGA RAO;VENKAIAH CHOWDARY NANNAPANENI |
| 分类号 |
C07D403/06;A61K31/404;A61P35/00 |
主分类号 |
C07D403/06 |
| 代理机构 |
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