| 发明名称 |
PYRIDO [2,3-D] PYRIMIDINE-2,4-DIAMINE COMPOUNDS AS PTP1B INHIBITORS |
| 摘要 |
The present invention is concerned with compounds of formula (I) wherein R1, R2, R3, R4 and X are as described in the description and claims. The compounds are inhibitors of PTP1B. Accordingly, the compounds can be used for treating or preventing PTP-1B mediated diseases, including diabetes, obesity, and diabetes-related diseases.
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| 申请公布号 |
CA2614443(C) |
申请公布日期 |
2011.03.22 |
| 申请号 |
CA20062614443 |
申请日期 |
2006.07.11 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BERTHEL, STEVEN JOSEPH;CHEUNG, ADRIAN WAI-HING;KIM, KYUNGJIN;LI, SHIMING;THAKKAR, KSHITIJ CHHABILBHAI;YUN, WEIYA |
| 分类号 |
C07D471/04;A61K31/519;A61P3/00 |
主分类号 |
C07D471/04 |
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