| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to crystalline forms of a hydrate of 5-(4-{[6-(4-amino-3,5-dimethylphenoxy)-1-methyl-1-H-benzimidazol-2-yl]methoxy}benzyl)-1,3-thiazolidine-2,4-dione dihydrochloride of formula (I). The invention also relates to methods for synthesis of said compounds and to pharmaceutical compositions based on said compounds, having PPARy activating property. ^ EFFECT: said forms of the compounds are more stable and can be used in medicine to prepare medicinal agents for treating diabetes, cancer accompanied by diabetes. ^ 16 cl, 7 tbl, 5 dwg, 6 ex |
