发明名称 |
COMPOSITIONS OF GNRH RELATED COMPOUNDS AND PROCESSES OF PREPARATION |
摘要 |
<p>The present invention provides compositions of GnRH related compounds that are suitable for oral administration, injectable administration and other forms of administration wherein the gelling characteristics of the composition are a factor. The compositions of the present invention comprise a therapeutically effective amount of one or more GnRH related compound, and a sufficient amount of at least one anti-gelling agents to reduce the gelation of the GnRH related compound. The present invention also provides processes for preparation of a composition of one or more GnRH related compound, wherein the process comprises mixing the GnRH related compound with one or more anti-gelling agents, wherein the anti-gelling agent comprises a medium chain fatty acid salt, or an ester, an ether, or a derivative of a medium chain fatty acid and has a carbon chain length of from about 4 to about 20 carbon atoms or is a surface active agent.</p> |
申请公布号 |
EP2288369(A1) |
申请公布日期 |
2011.03.02 |
申请号 |
EP20090743067 |
申请日期 |
2009.05.07 |
申请人 |
MERRION RESEARCH III LIMITED |
发明人 |
LEE, AMANDA;ADAMCZYK, BOZENA;COUGHLAN, DAVID, C.;O'TOOLE, EDEL;LEONARD, THOMAS, W. |
分类号 |
A61K9/48;A61K9/28;A61K38/09;A61K47/06;A61K47/12;A61K47/14;A61P5/24 |
主分类号 |
A61K9/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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