发明名称 |
SCREENING OF PROTEIN CANDIDATES |
摘要 |
Successful application of an engineered protein as therapeutics or in other industries would require the protein to have good expression level, good biophysical properties and often desired affinity to its target. The present invention provides s method of screening large numbers of protein candidates (PCs) in all three aspects simultaneously. PCs are fused to a protein anchor, which is captured by the target/antigen. The captured PCs are evaluated for their expression levels, biophysical properties and affinities using conventional methods. |
申请公布号 |
WO2011020183(A1) |
申请公布日期 |
2011.02.24 |
申请号 |
WO2010CA01267 |
申请日期 |
2010.08.18 |
申请人 |
NATIONAL RESEARCH COUNCIL CANADA;ZHANG, JIANBING;HIRAMA, TOMOKO |
发明人 |
ZHANG, JIANBING |
分类号 |
C12N15/62;C07K19/00;C40B30/00;G01N33/68 |
主分类号 |
C12N15/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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