发明名称 |
Isolated mutant protein of fibroblast growth factor 18 and pharmaceutical composition comprising the same |
摘要 |
Disclosed is a mutant protein having an altered fibroblast growth factor receptor specificity, which is produced by deleting one or more amino acid residues from the N-terminus of the amino acid sequence of naturally secreted fibroblast growth factor 18. The protein mutant can be used in a pharmaceutical composition for regulating hair regeneration or growth or a pharmaceutical composition for regulating bone or cartilage formation.
|
申请公布号 |
US7893028(B2) |
申请公布日期 |
2011.02.22 |
申请号 |
US20070159854 |
申请日期 |
2007.01.09 |
申请人 |
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCEAND TECHNOLOGY |
发明人 |
IMAMURA TORU;TSUJINO NOZOMI;SUZUKI MASASHI;ASADA MASAHIRO |
分类号 |
A61K38/18;C07K14/50 |
主分类号 |
A61K38/18 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|