发明名称 |
IMMUNOGENIC COMPOSITION COMPRISING ANTIGENIC S. AUREUS PROTEINS |
摘要 |
The present application relates to an immunogenic composition comprising a fragment of a staphylococcal lsd protein such as IsdA, IsdB, IsdC or IsdH which comprises a NEAT domain. Fusion proteins comprising a NEAT domain of a first staphylococcal lsd protein and a NEAT domain from a second lsd protein are also disclosed as well as fusion proteins comprising a NEAT domain of a staphylococcal lsd protein involved in an iron/heme uptake system and a ligand binding domain of a staphylococcal extracellular component binding protein, for example CIfA, CIfB, SdrC, SdrD or SdrE.
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申请公布号 |
CA2769610(A1) |
申请公布日期 |
2011.02.10 |
申请号 |
CA20102769610 |
申请日期 |
2010.08.03 |
申请人 |
GLAXOSMITHKLINE BIOLOGICALS S.A. |
发明人 |
CASTADO, CINDY;GERMAIN, SOPHIE MARIE JEANNE VALENTINE;GILBERT, MELANIE |
分类号 |
A61K39/085;A61K39/116;C12N15/62 |
主分类号 |
A61K39/085 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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