发明名称 |
COMPOSITIONS AND METHODS FOR CANCER GENE DISCOVERY |
摘要 |
The present invention features transgenic non-human mammalian animals being genetically modified to develop cancer. The invention also relates to methods for identifying genes or genetic elements that are potentially related to human cancers using an chromosomally unstable animal model. Information on such genetic alterations can be used to predict cancer therapeutic outcomes and to stratify patient populations to maximize therapeutic efficacy. |
申请公布号 |
US2011030074(A1) |
申请公布日期 |
2011.02.03 |
申请号 |
US20080601052 |
申请日期 |
2008.05.21 |
申请人 |
DANA FARBER CANCER INSTITUTE, INC. |
发明人 |
DEPINHO RONALD A.;CHIN LYNDA;MASER RICHARD |
分类号 |
A01K67/027;A61K39/395;A61P35/00;C12Q1/02;C12Q1/68 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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