发明名称 |
REPROGRAMMING A CELL BY INDUCING A PLURIPOTENT GENE THROUGH USE OF AN HDAC MODULATOR |
摘要 |
<p>The invention relate to methods, compositions, and kits for reprogramming a cell. In one embodiment, the invention relates to a method comprising inducing the expression of at least one gene that contributes to a cell being pluripotent or multipotent. In yet another embodiment, the method comprises exposing a cell to a small molecule modulator that induces the expression of at least one gene that contributes to a cell being pluripotent or multipotent. In yet another embodiment, the invention relates to a reprogrammed cell and an enriched population of reprogrammed cells that can have characteristics of an ES-like cell can be re- or trans-differentiated into various differentiated cell types.</p> |
申请公布号 |
EP2274424(A2) |
申请公布日期 |
2011.01.19 |
申请号 |
EP20090729724 |
申请日期 |
2009.04.07 |
申请人 |
NUPOTENTIAL, INC. |
发明人 |
EILERTSEN, KENNETH, J.;POWER, RACHEL, A.;RIM, JONG, S. |
分类号 |
C12N15/113;A61K31/00;C12N5/00 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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