| 发明名称 |
TETRAHYDROPHENANTHRIDINONES AND TETRAHYDROCYCLOPENTAQUINOLINONES AS PARP AND TUBULIN POLYMERIZATION INHIBITORS |
| 摘要 |
<p>The present invention provides compounds of formula (I), their use as inhibitors of tubulin polymerization and their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7 and Y have defined meanings.</p> |
| 申请公布号 |
EP2271626(A1) |
申请公布日期 |
2011.01.12 |
| 申请号 |
EP20090725177 |
申请日期 |
2009.03.26 |
| 申请人 |
JANSSEN PHARMACEUTICA, N.V. |
发明人 |
ANGIBAUD, PATRICK RENE;MEVELLEC, LAURENCE, ANNE;ROUX, BRUNO;STORCK, PIERRE-HENRI;MEYER, CHRISTOPHE;VIALARD, JORGE EDUARDO |
| 分类号 |
C07D221/12;A61K31/473;A61P35/00;C07D401/06 |
主分类号 |
C07D221/12 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
