发明名称 |
LYOPHILIZED FORMULATIONS FOR SMALL MODULAR IMMUNOPHARMACEUTICALS |
摘要 |
<p>The present invention provides, among other things, stable formulations for small modular immunopharmaceutical (SMIPTM) proteins. In some embodiments, the present invention provides a formulation containing a lyophilized mixture of a small modular immunopharmaceutical protein, wherein less than 7% of the lyophilized small modular immunopharmaceutical protein exists in aggregated form. Formulations according to the invention may contain buffering agents, stabilizers, bulking agents, surfactants and/or other excipients. The present invention also provides formulations for lyophilization, reconstitution and methods of use thereof.</p> |
申请公布号 |
WO2010148337(A1) |
申请公布日期 |
2010.12.23 |
申请号 |
WO2010US39227 |
申请日期 |
2010.06.18 |
申请人 |
WYETH LLC;TCHESSALOV, SERGUEI;KANTOR, ANGELA;LI, LI;LUKSHA, NICHOLAS;WARNE, NICHOLAS |
发明人 |
TCHESSALOV, SERGUEI;KANTOR, ANGELA;LI, LI;LUKSHA, NICHOLAS;WARNE, NICHOLAS |
分类号 |
A61K9/19 |
主分类号 |
A61K9/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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