| 发明名称 |
1-BENZYL-3-HYDROXYMETHYLINDAZOLE DERIVATIVES AND USE THEREOF IN THE TREATMENT OF DISEASES BASED ON THE EXPRESSION OF MCP-1, CX3CR1. |
| 摘要 |
<p>The present invention relates to novel 1 -benzyl-3-hydroxymethylindazole derivatives according to formula (I) described in the claims, and to a pharmaceutical composition comprising them, together with a pharmaceutically acceptable vehicle. In addition, the present invention relates to the use of 1 -benzyl-3-hydroxymethylindazole derivatives for the preparation of a pharmaceutical composition that is active in the treatment of diseases based on the expression of MCP-1, CX3CR1 and p40, and to their use in a method for treating or preventing diseases based on the expression of MCP-1, CX3CR1 and p40.</p> |
| 申请公布号 |
MX2010009626(A) |
申请公布日期 |
2010.12.20 |
| 申请号 |
MX20100009626 |
申请日期 |
2009.03.05 |
| 申请人 |
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. |
发明人 |
NICOLA CAZZOLLA;ANGELO GUGLIELMOTTI;GUIDO FURLOTTI;GIORGINA MANGANO;BARBARA GAROFALO |
| 分类号 |
C07D231/56;A61K31/415;A61P13/00;A61P25/00;A61P29/00 |
主分类号 |
C07D231/56 |
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