发明名称 |
ANTIBODIES SPECIFIC TO CADHERIN-17 |
摘要 |
The present disclosure provides antibodies, including isolated monoclonal antibodies, which specifically bind to Cadherin-17 with high affinity. Nucleic acid molecules encoding Cadherin-17 antibodies, expression vectors, host cells and methods for expressing the Cadherin-17 antibodies are also provided. Bispecific molecules and pharmaceutical compositions comprising the Cadherin-17 antibodies are also provided. Methods for detecting Cadherin-17, as well as methods for treating various cancers, including colorectal cancer, are disclosed. |
申请公布号 |
WO2010123874(A1) |
申请公布日期 |
2010.10.28 |
申请号 |
WO2010US31719 |
申请日期 |
2010.04.20 |
申请人 |
OXFORD BIOTHERAPEUTICS LTD.;ROHLFF, CHRISTIAN;TERRETT, JONATHAN, ALEXANDER |
发明人 |
ROHLFF, CHRISTIAN;TERRETT, JONATHAN, ALEXANDER |
分类号 |
C07K16/28;G01N33/574 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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