发明名称 INDOLIZINE DERIVATIVE AND USE THEREOF FOR MEDICAL PURPOSES
摘要 Disclosed is a compound useful as a prophylactic or therapeutic agent for diseases associated with the abnormality of serum uric acid levels and other diseases. Specifically disclosed are: an indolizine derivative represented by formula (I) or a prodrug or a salt thereof, which has an inhibitory activity on xanthine oxidase and is useful as a prophylactic or therapeutic agent for diseases associated with the abnormality of serum uric acid levels; and others. In the formula, ring U represents an aryl group, or a heteroaryl group; R1 represents a halogen atom, a hydroxy group, or the like; R2 represents a halogen atom, a hydroxy group, an alkyl group, an alkoxy group, an alkyl group substituted by a fluorine atom, an alkoxy group substituted by a fluorine atom, or the like; m represents 0 to 2; n represents 0 to 3; and R3 represents a hydrogen atom, a fluorine atom, or the like.
申请公布号 CA2755132(A1) 申请公布日期 2010.10.07
申请号 CA20102755132 申请日期 2010.03.30
申请人 KISSEI PHARMACEUTICAL CO., LTD. 发明人 SHIMIZU, KAZUO;IIZUKA, MASATO;TAKIGAWA, YASUSHI
分类号 C07D471/04;A61K31/437;A61P13/02;A61P13/12;A61P19/02;A61P19/06;A61P43/00 主分类号 C07D471/04
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