发明名称 CANCEROUS DISEASE MODIFYING ANTIBODIES
摘要 <p>The present invention relates to a method for producing patient cancerous disease modifying antibodies using a novel paradigm of screening. By segregating the anti-cancer antibodies using cancer cell cytotoxicity as an end point, the process makes possible the production of anti-cancer antibodies for therapeutic and diagnostic purposes. The antibodies can be used in aid of staging and diagnosis of a cancer, and can be used to treat primary tumors and tumor metastases. The anti-cancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematogenous cells.</p>
申请公布号 SI1718737(T1) 申请公布日期 2010.09.30
申请号 SI20050031076T 申请日期 2005.02.28
申请人 F. HOFFMANN-LA ROCHE AG 发明人 YOUNG DAVID S. F.;HAHN SUSAN E.;CECHETTO LISA M.
分类号 A61K39/395;A61K51/10;A61P35/00;C07K16/18;C07K16/30;C12N5/12;C12N5/18;C12Q1/68;G01N33/574 主分类号 A61K39/395
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