PROCESS FOR PRODUCING 4-CHLOROAZETIDINONE COMPOUND
摘要
<p>Disclosed is a process for producing a 4-chloroazetidinone compound, which is a compound useful as an intermediate for the synthesis of a carbapenem antibiotic, with high efficiency and in a high yield. Also disclosed is an intermediate which can be used as a starting material in the process. Specifically disclosed is a process for producing a 4-chloroazetidinone compound represented by general formula (1) [wherein R1 represents a hydrogen atom or a protective group for a hydroxy group] by chlorinating the fourth position in a 4-dithioazetidinone compound represented by general formula (2) [wherein R1 is as defined in above; and R3 represents a heterocyclic group].</p>
申请公布号
WO2010095617(A1)
申请公布日期
2010.08.26
申请号
WO2010JP52285
申请日期
2010.02.16
申请人
OTSUKA CHEMICAL CO., LTD.;TANAKA, HIDEO;KUROBOSHI, MANABU;ITO, OSAMU;YUASA, HIROAKI