发明名称 PHARMACEUTICAL FORMULATION FOR THE PRODUCTION OF RAPIDLY DISINTERGRATING TABLETS
摘要 Pharmaceutical formulation in the form of compacts comprising A) an agglomerated excipient content composed of a1) 60-97% by weight of sugar or sugar alcohols, a2) 1-25% by weight of a disintegrant, selected from the group consisting of crospovidone, croscarmellose, sodium carboxymethylstarch and L-hydroxypropylcellulose, a3) 1-15% by weight of water-insoluble, film-forming polymers a4) 0-15% by weight of water-soluble polymers and a5) 0-15% by weight of further pharmaceutically customary excipients, the total of the components a1) to a5) being 100% by weight, B) at least one active ingredient, C) 0 to 10% by weight, based on the total amount of A) to D), of a lubricant or mold release agent, and D), if appropriate, further pharmaceutical excipients.
申请公布号 US2010173859(A1) 申请公布日期 2010.07.08
申请号 US20080663036 申请日期 2008.06.02
申请人 BASF SE 发明人 KOLTER KARL;SCHOENHERR MICHAEL;GEBERT SILKE;MEYER-BOEHM KATHRIN;MASCHKE ANGELIKA
分类号 A61K31/7052;A61K31/4196;A61K31/422;A61K31/4402;A61K31/551;A61K31/5513;A61P43/00 主分类号 A61K31/7052
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